The advent of nanozyme has changed the traditional concept that inorganic nano materials are a biological inert material, revealed the internal biological effects and new characteristics of nano materials, enriched the research of simulated enzyme, expanded it from organic composites to inorganic nano materials, and expanded the application range of nano materials. In view of the high catalytic activity of natural enzymes and the stable and economic characteristics of simulated enzymes, since the report of HRP like enzyme activity nano enzymes in 2007, the research of nano enzymes has risen rapidly and gradually covered a wide range, including different fields such as material science, physics, chemistry, biology, medicine, and environment.